Medscape Pathology & Lab Medicine Headlines

Why and How to Use the Photographic Atlases of the American Registry of Pathology

Fri, 10 Oct 2008 08:43:16 EDT

William A. Gardner, MD, Executive Director, American Registry of Pathology, Silver Spring, Maryland, describes the importance of visual images to medicine.
The Medscape Journal of Medicine

Talc Use in Genital Area Linked to Increased Risk for Ovarian Cancer

Fri, 10 Oct 2008 17:00:00 EDT

Women should avoid using talc in the genital area, say researchers reporting further evidence supporting an association between such use and an increase in the risk for ovarian cancer.
Medscape Medical News

Overweight, High C-Peptide May Predict Future Mortality From Prostate Cancer

Fri, 10 Oct 2008 17:00:00 EDT

Both excess body weight and a high plasma concentration of C-peptide predispose men with a subsequent diagnosis of prostate cancer to an increased likelihood of dying of this disease.
Medscape Medical News

Mild Glucose Abnormalities in Pregnancy Linked to Postpartum Diabetes Risk

Fri, 10 Oct 2008 17:00:00 EDT

A study shows that any degree of abnormal glucose homeostasis during pregnancy is predictive of glucose intolerance 3 months after delivery.
Reuters Health Information

DNA Stool Tests Show Promise for Colorectal Cancer Screening

Thu, 9 Oct 2008 08:15:00 EDT

A second-generation stool DNA test proved to be more sensitive in detecting malignant and premalignant lesions than widely used fecal occult blood tests.
Medscape Medical News

H. Pylori Vaccine Passes Phase 1 Testing

Fri, 10 Oct 2008 11:18:57 EDT

An intramuscular Helicobacter pylori vaccine showed "satisfactory safety and immunogenicity, produced antigen-specific T-cell memory, and, therefore, warrants further clinical study," researchers report in the September issue of Gastroenterology.
Reuters Health Information

Ginkgo Extract May Reduce Stroke Damage

Fri, 10 Oct 2008 11:35:03 EDT

The results of an animal study suggest that use of Ginkgo biloba extract EGb761 before or after a stroke can reduce the size of the infarct and potentially improve neurologic function. The compound appears to achieve this effect, at least in part, by enhancing an endogenous antioxidant system.
Reuters Health Information

A 14-Year-Old Boy With Progressive Weakness and Dyspnea

Wed, 8 Oct 2008 12:00:00 EDT

A 14-year-old boy presents to the ED with a 10-day history of progressive weakness following symptoms of an upper respiratory infection. The patient’s weakness is affecting his extremities, and he has developed shortness of breath and difficulty urinating. The patient is sent for magnetic resonance imaging (MRI) of his brain and spine. What is the patient’s condition as verified by the MRI?
eMedicine Case Presentations

Role of Human Papillomavirus Types 16, 18, and 52 in Recurrent Cystitis and Urinary Bladder Cancer Among Egyptian Patients

Wed, 8 Oct 2008 08:57:04 EDT

We estimated the prevalence of HPV-16, -18, and -52 in bladder cancer or recurrent cystitis and studied the correlation of type-specific HPV-IgG with PCR results and clinicopathologic parameters.
The Medscape Journal of Medicine

Genetic Variant Tied to Pediatric Liver Transplant Rejection

Thu, 9 Oct 2008 11:58:24 EDT

A single nucleotide polymorphism (SNP) in a major histocompatibility complex-linked gene appears to be associated with early liver transplant rejection in children, Pennsylvania-based researchers report in the September issue of Gastroenterology.
Reuters Health Information

Genetic Testing Worthwhile in HIV Abacavir Candidates

Wed, 8 Oct 2008 10:29:24 EDT

Genetic screening for the allele HLA-B*5701 is advisable before abacavir treatment is started in patients with HIV infection, researchers report in the October 1st issue of AIDS.
Reuters Health Information

First Major Gene Reported for Autosomal Recessive Retinitis Pigmentosa

Mon, 6 Oct 2008 11:34:37 EDT

Independent mutations in a newly identified gene, EYS, are present in unrelated families with retinitis pigmentosa.
Medscape Medical News

New Finding May Improve Diagnosis of Juvenile Leukemia

Mon, 6 Oct 2008 12:59:56 EDT

An abnormal signaling pathway that appears to be highly specific to juvenile myelomonocytic leukemia could allow for more rapid and accurate diagnosis and targeted therapies.
Medscape Medical News

Scientists Discover Neuroblastoma Gene

Mon, 6 Oct 2008 13:39:00 EDT

The author discusses new findings about a genetic cause of neuroblastoma.
Medscape Genomic Medicine

Genomewide Study of Ulcerative Colitis Identifies Variants Contributing to Disease Susceptibility

Mon, 6 Oct 2008 15:43:00 EDT

The gene for interleukin 10, an immunosuppressive cytokine, plays a clear role in ulcerative colitis susceptibility.
Medscape Medical News

AIDS Pioneers, Cancer Researcher Win Nobel Prize

Tue, 7 Oct 2008 10:20:10 EDT

Two French scientists who discovered the human immunodeficiency virus and a German who identified human papilloma virus as the cause of cervical cancer were awarded the 2008 Nobel prize for medicine or physiology on Monday.
Reuters Health Information

Genetic Differences May Account for Racial Disparities in Asthma Severity

Tue, 7 Oct 2008 10:25:18 EDT

Asthma patients who are black tend to have more severe disease than asthma patients who are white, leading to more asthma control problems, higher rates of emergency department visits, and overall worse quality of life. These findings from a large, prospective cohort study point to genetic and pharmacogenetic differences as the source of these racial disparities.
Reuters Health Information

Genetic Variation in Complement Regulator Linked to AMD

Tue, 7 Oct 2008 10:59:19 EDT

Genetic variation in the serpin peptidase inhibitor, clade G member 1 (SERPING1) is associated with age-related macular degeneration (AMD), according to cohort studies conducted in the UK and the US.
Reuters Health Information

Vitamin D Analog May Improve Treatment of Diabetic Nephropathy

Tue, 7 Oct 2008 11:11:14 EDT

Combining a vitamin D analog with an angiotensin II type 1 receptor blocker can further reduce the renal injury seen with diabetic nephropathy, the results of an animal study suggest.
Reuters Health Information

Salivary Proteomics Identifies Oral Squamous Cell Carcinoma Biomarkers

Tue, 7 Oct 2008 14:24:03 EDT

Protein patterns in saliva may be able to identify patients with oral squamous cell carcinoma (OSCC), according to a report in the October 1st Clinical Cancer Research.
Reuters Health Information