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Universal Primer PCR Test May Aid in Diagnosis of Neonatal Sepsis
A prospective study showed that universal primer polymerase chain reaction was accurate in diagnosing neonatal sepsis before but not after antibiotic therapy.
Medscape Medical News, January 2009
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FDA Approves First Nucleic Acid Test to Screen for 2 Divergent HIV Types
The US Food and Drug Administration has approved the cobas TaqScreen MPX test for the presence of 2 divergent types of HIV in donated blood plasma and tissue.
Medscape Medical News, January 2009
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Alternative Vaccine Schedule Stirs Debate
An article in Pediatrics criticizes a popular book on the timing of children's vaccines.
WebMD Health News, January 2009
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CME/CE
Selective Digestive, Oropharyngeal Decontamination May Reduce Intensive Care Mortality
In an intensive care unit, mortality rate was reduced by 3.5 percentage points with selective digestive tract decontamination and by 2.9 percentage points with selective oropharyngeal decontamination.
Medscape Medical News, January 2009
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Ability of Tea Tree Oil Body Wash to Prevent MRSA Colonization to Be Tested
A new study will investigate whether a tea tree oil (TTO) body wash can prevent methicillin-resistant Staphylococcus aureus (MRSA) colonization in critically ill adults, according to a report issued online November 28 by BMC Infectious Diseases.
Reuters Health Information, January 2009
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HIV Drug Resistance Less Likely With Experimental Protease Inhibitor
An in vitro selection study shows that PL-100, a novel HIV-1 protease inhibitor (PI) has a high genetic barrier to resistance, Canadian and US researchers report in the December issue of the Journal of Medical Virology.
Reuters Health Information, January 2009
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TNF Blockers Affect Macrophage Response to TB
Tumor necrosis factor (TNF) blockers interfere with the macrophage response to Mycobacterium tuberculosis by suppressing maturation of phagosomes, according to a report in the December 15th issue of The Journal of Infectious Diseases.
Reuters Health Information, January 2009
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HPV-16 Oncoprotein Vaccine Protects Against Head and Neck Cancer in Mice
Immunization with a vaccine that targets the E6 and E7 oncoproteins of human papillomavirus-16 (HPV-16) prevents mice with HPV-16-positive head and neck squamous cell cancers (HNSCCs) from expressing these two oncoproteins by mounting a potent immune response.
Reuters Health Information, January 2009
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Late-Onset Group B Strep Prevention "Warrants Renewed Attention"
The burden of late-onset group B streptococcal (GBS) disease "remains substantial" in the United States, research shows. Preventing late-onset GBS disease "will likely require a multipronged strategy, including vaccination," the research team concludes in the December issue of The Pediatric Infectious Disease Journal.
Reuters Health Information, January 2009
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Linear Herpes Ulcers: the "Knife-Cut Sign"
In immunocompromised patients, herpes simplex virus (HSV) may present as linear intertriginous fissures similar to the "knife-cut" ulcers associated with metastatic Crohn's disease, clinicians from New York have observed.
Reuters Health Information, January 2009
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Phage-Mediated Transfer of Gene Elements Not Limited to "Related" Bacteria
Bacteria can transfer genetic material, via bacteriophages, not just within their own species but also to bacteria that are not closely related, researchers have discovered.
Reuters Health Information, January 2009
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Childhood and Adolescent Immunization Schedules Revised
The American Academy of Pediatrics, Advisory Committee on Immunization Practices, and American Academy of Family Physicians endorse the 2009 immunization recommendations.
Medscape Medical News, December 2008
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Selective Digestive, Oropharyngeal Decontamination May Reduce Intensive Care Mortality
In an intensive care unit, mortality rate was reduced by 3.5 percentage points with selective digestive tract decontamination and by 2.9 percentage points with selective oropharyngeal decontamination.
Medscape Medical News, December 2008
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Endemic Hepatitis E Not Confined to Tropics
Hepatitis E virus (HEV) infection is endemic in Germany, where it probably exists as a food-borne zoonosis, according to a report in the December 15th issue of The Journal of Infectious Diseases.
Reuters Health Information, December 2008
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Most Children Recover From Lyme Neuroborreliosis Without Sequelae
Clinical recovery is usually satisfactory in children treated for Lyme neuroborreliosis, and subsequent fatigue or headache are not attributable to the condition, according to a report in the December issue of The Pediatric Infectious Disease Journal.
Reuters Health Information, December 2008
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Oral Cholecalciferol/Calcium Regimen Seen Effective in HIV-Infected Children
In HIV-infected children and adolescents, bimonthly supplementation with oral doses of cholecalciferol together with daily calcium leads to a significant increase in serum 25-hydroxyvitamin D (25-OHD) concentrations and is well tolerated, a group of clinicians from New York City has found.
Reuters Health Information, December 2008
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CME
Prolonged Empiric Antibiotics May Increase Risk for Necrotizing Enterocolitis in Certain Infants
In extremely-low-birth-weight infants, prolonged initial empiric antibiotics should be used with caution because they may be associated with an increased risk for necrotizing enterocolitis or death.
Medscape Medical News, December 2008
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Prolonged Empiric Antibiotics May Increase Risk for Necrotizing Enterocolitis in Certain Infants
In extremely-low-birth-weight infants, prolonged initial empiric antibiotics should be used with caution because they may be associated with an increased risk for necrotizing enterocolitis or death.
Medscape Medical News, December 2008
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HIV-TB Co-Infection in Infants a Major Burden in South Africa
HIV-positive infants are over 20 times more likely to develop tuberculosis than their HIV-negative counterparts, researchers from South Africa report in the January 1st issue of Clinical Infectious Diseases.
Reuters Health Information, December 2008
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MRSA Colonization Common in Emergency Department Personnel
Health care workers in the emergency department are often colonized with methicillin-resistant Staphylococcus aureus (MRSA), potentially putting patients at risk, according to two reports in the November issue of the Annals of Emergency Medicine.
Reuters Health Information, December 2008
