-
ASHG 2008: Many Squamous Cell Tumors in Organ Transplant Recipients Contain Nonrecipient DNA
Extra alleles are often present in cutaneous squamous cell carcinomas of organ transplant recipients.
Medscape Medical News, November 2008
-
AACR FCPR 2008: Genetic Markers May Identify Prostate Cancer Risk
Five genetic risk markers might help identify men at the highest risk for a diagnosis of prostate cancer and help tailor and individualize screening.
Medscape Medical News, November 2008
-
ASHG 2008: Gaucher Disease Mutation Carriers at Higher Risk for Parkinson's Disease
A multiethnic study on 4 continents found that glucocerebrosidase gene mutations are the most common genetic risk factor for Parkinson's disease.
Medscape Medical News, November 2008
-
CME
Management of Acinetobacter baumannii Reviewed
A review of the current control and treatment of Acinetobacter baumannii notes that this frequently antimicrobial drug-resistant infection occurs in many critically ill hospitalized patients.
Medscape Medical News, November 2008
-
CME
Genetic Screening May Only Modestly Improve Detection of Type 2 Diabetes
A cohort study shows that genetic screening based on 18 risk alleles only modestly improves detection of type 2 diabetes and that traditional risk factors are as effective to identify the disease.
Medscape Medical News, November 2008
-
1st Trachea Transplant From Stem Cells
European doctors have used their patient's own stem cells to prepare a donor's trachea.
WebMD Health News, November 2008
-
Counseling May Reduce Clinician Burnout and Stress
A short-term counseling intervention was effective in reducing burnout and stress in a cohort of Norwegian clinicians.
Medscape Medical News, November 2008
-
ASHG 2008: Six New Loci Associated With Serum Lipid Levels
In a genomewide association study, 3 of the 22 genomic regions associated with serum lipid levels affect men and women differently.
Medscape Medical News, November 2008
-
Growth Hormone Secretagogue MK-677 Ineffective in Alzheimer's Disease
A randomized trial of MK-677, a growth hormone secretagogue, shows no benefit for patients with Alzheimer's disease, despite successfully increasing serum insulinlike growth factor-1, the treatment target in this trial.
Medscape Medical News, November 2008
-
Imaging Study Provides Strong Support for Cognitive-Reserve Hypothesis
A new imaging study looking at plaque burden in the brains of individuals with and without dementia strongly supports the long-held cognitive-reserve hypothesis, that those with more education are better able to withstand Alzheimer's disease pathology.
Medscape Medical News, November 2008
-
Cryptorchidism Linked to Specific Genetic Mutations
A case-control study showed that bilateral and persistent cryptorchidism was associated with genetic mutations, including Klinefelter syndrome and INSL3 receptor gene mutations.
Medscape Medical News, November 2008
-
CME
Doxycycline, Tetracycline May Be Effective for Syphilis Treatment
A Canadian study shows that doxycycline or tetracycline has a similarly high serologic treatment success rate vs benzathine penicillin in the treatment of primary syphilis.
Medscape Medical News, November 2008
-
Widespread MHC II Molecule Exchange Seen After Solid Organ Transplant
There is extensive bidirectional transfer of major histocompatibility complex (MHC) class II molecules between donor and recipient cells after solid organ transplantation in mice, according to a report in the November issue of The FASEB Journal.
Reuters Health Information, November 2008
-
Celiac Disease: Faster Gluten Test
A new test can detect the gluten protein gliadin in food in 90 minutes versus the current method that takes 8 hours.
WebMD Health News, November 2008
-
ASHG 2008: Human Chromosome 4 Variants Associated With Increased Risk for Atrial Fibrillation
Polymorphisms linked to a higher risk for postoperative atrial fibrillation do not include the coding region of candidate gene PITX2.
Medscape Medical News, November 2008
-
ASHG 2008: 1000 Genomes Project Vastly Expands Map of Human Genome Variation
Each week, in recent months, this international public–private consortium has produced an amount of information equivalent to GenBank.
Medscape Medical News, November 2008
-
CME/CMLE
ASHG 2008: Genomewide Association Study Finds Genetic Predictors of Warfarin Required Dose
Genetic information enables researchers to predict 50% or more of individual variation in required warfarin dosage.
Medscape Medical News, November 2008
-
CME
Calcium and Vitamin D Not Protective Against Breast Cancer but Hope Remains
Calcium and vitamin D supplements do not appear to reduce breast cancer incidence in postmenopausal women.
Medscape Medical News, November 2008
-
ASHG 2008: Increased Gene Expression Improves Neurologic Function in Mouse Model of Huntington's Disease
Overexpression of PGC-1alpha decreased the aggregation of mutant huntingtin protein in neuronal nuclei.
Medscape Medical News, November 2008
-
ASN 2008: Gene Variants May Help Identify African Americans at Risk for Kidney Disease
New research suggests that common gene variations on the MYH9 gene is linked to an elevated risk for kidney disease in African Americans, and the data may provide a key to early screening and potential disease prevention.
Medscape Medical News, November 2008