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Universal Primer PCR Test May Aid in Diagnosis of Neonatal Sepsis
A prospective study showed that universal primer polymerase chain reaction was accurate in diagnosing neonatal sepsis before but not after antibiotic therapy.
Medscape Medical News, January 2009
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Excessive Daytime Sleepiness More Common in Obese Children With Habitual Snoring
A study shows that the likelihood of excessive daytime sleepiness in obese children is greater vs nonobese children at any given level of severity of obstructive sleep apnea.
Medscape Medical News, January 2009
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CME
Second-Generation Antipsychotics Not All Superior to Older Drugs
In a current meta-analysis, only half of second-generation antipsychotic medications were found to be more effective for schizophrenia and reduce symptomatic relapse vs first-generation drugs.
Medscape Medical News, January 2009
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CME
Excessive Daytime Sleepiness More Common in Obese Children With Habitual Snoring
A study shows that the likelihood of excessive daytime sleepiness in obese children is greater vs nonobese children at any given level of severity of obstructive sleep apnea.
Medscape Medical News, January 2009
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CME/CE
Spinal Surgery Superior to Exercise, Medical Therapy at 4 Years
A new analysis extends to 4-year follow-up showing that spine surgery provides more rapid and greater relief of symptoms and improvement in function vs nonsurgical options for lumbar disc herniation.
Medscape Medical News, January 2009
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Psoriasis and CAD: New Call to Recognize Link
A new report is reiterating the increased risk of coronary artery disease observed in patients with the inflammatory skin disease psoriasis and stressing that patients must be informed of this link and have their cardiovascular risk factors regularly assessed and, if necessary, treated.
Heartwire, January 2009
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No Antiarrhythmic Protection With Fish Oil, New Meta-Analysis Shows
The analysis, driven primarily by the results of two large clinical trials, showed that fish oil was associated with a significant 20% reduction in the risk of cardiac death but did not reduce the incidence of appropriate ICD interventions or sudden cardiac death.
Heartwire, January 2009
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Second-Generation Antipsychotics Not All Superior to Older Drugs
A meta-analysis finds that only 4 of 9 second-generation antipsychotics were more efficacious than first-generation antipsychotics for schizophrenia, with small to medium effect sizes.
Medscape Medical News, January 2009
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FDA Approves First Nucleic Acid Test to Screen for 2 Divergent HIV Types
The US Food and Drug Administration has approved the cobas TaqScreen MPX test for the presence of 2 divergent types of HIV in donated blood plasma and tissue.
Medscape Medical News, January 2009
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Prasugrel FDA Hearing Set for February 3, 2009
An FDA advisory committee will review prasugrel for the treatment of ACS patients who are managed with PCI on February 3, 2009. Separately, the FDA has also said it may consider changing the label for clopidogrel following studies published last week that show it might not be effective in up to 30% of patients.
Heartwire, January 2009
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Recalls & Warnings FDA Warns That Tinzaparin Increases Mortality Risk in Elderly Patients With Renal Insufficiency
A clinical study indicated that tinzaparin may lead to an increased risk for death in all renal-impaired elderly patients receiving tinzaparin.
Medscape Medical News, January 2009
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CME
CAFE-LLA: Statin Therapy Does Not Influence Central Aortic Pressure or Hemodynamics
Statins are beneficial in patients with hypertension but have no effect on central aortic pressures, pulse-wave augmentation, or any other central hemodynamic parameter.
Medscape Medical News, January 2009
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CME
Routine Cystoscopy After Hysterectomy Identifies "Silent" Urinary Tract Injuries
Universal intraoperative cystoscopy after a hysterectomy allows immediate repair of injuries to the ureter and bladder that would otherwise go undetected, according to a study.
Reuters Health Information, January 2009
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CME/CE
Selective Digestive, Oropharyngeal Decontamination May Reduce Intensive Care Mortality
In an intensive care unit, mortality rate was reduced by 3.5 percentage points with selective digestive tract decontamination and by 2.9 percentage points with selective oropharyngeal decontamination.
Medscape Medical News, January 2009
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CME
FDA Safety Changes: Clolar, Precedex, Treanda
The FDA has approved revisions to the safety labeling for clofarabine injection (Clolar), dexmedetomidine HCl injection (Precedex), and bendamustine HCl injection (Treanda).
Medscape Medical News, January 2009
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FDA Safety Changes: Clolar, Precedex, Treanda
The FDA has approved revisions to the safety labeling for clofarabine injection (Clolar), dexmedetomidine HCl injection (Precedex), and bendamustine HCl injection (Treanda).
Medscape Medical News, January 2009
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HIV Drug Resistance Less Likely With Experimental Protease Inhibitor
An in vitro selection study shows that PL-100, a novel HIV-1 protease inhibitor (PI) has a high genetic barrier to resistance, Canadian and US researchers report in the December issue of the Journal of Medical Virology.
Reuters Health Information, January 2009
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Noscapine May Be Effective for Prostate Cancer
Oral administration of noscapine may be useful in treating advanced prostate cancer, according to experimental findings published in the December issue of Anticancer Research.
Reuters Health Information, January 2009
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Benzbromarone More Effective and Better Tolerated Than Allopurinol for Gout
Benzbromarone may be more effective and better tolerated than allopurinol for lowering uric acid levels in gout patients, Dutch investigators report in the January Annals of the Rheumatic Diseases.
Reuters Health Information, January 2009
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Bioadhesive Bromocriptine Discs Effective for Treating Hyperprolactinemia
Buccoadhesive and vaginoadhesive discs containing bromocriptine mesylate are effective for treating pathologic hyperprolactinemia, according to researchers based in Egypt.
Reuters Health Information, January 2009
