BMC Nephrology publishes original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology. All research articles in BMC Nephrology, and other BioMed Central journals, are made available under an open access license, allowing free access, redistribution and reuse.
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Serum Free Light Chain Measurement Aids the Diagnosis of Myeloma in Patients With Severe Renal Failure
Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have now been adopted into screening algorithms for multiple myeloma .
Journal Article, September 2008
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Association of Kidney Function With Inflammatory and Procoagulant Markers in a Diverse Cohort: A Cross-Sectional Analysis From the Multi-Ethnic Study of Atherosclerosis (MESA)
Six inflammatory and procoagulant biomarkers were correlated with kidney function measures in multi-ethnic patients to replicate results from similar studies in non-diverse populations.
Journal Article, August 2008
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Oxpentifylline Versus Placebo in the Treatment of Erythropoietin-resistant Anaemia: A Randomized Controlled Trial
Anemia is a common problem in chronic kidney disease (CKD) but treatments are only marginally effective. Oxpentifylline is being studied as a new therapy for erythropoietin-resistant anaemia.
Journal Article, August 2008
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Sensitivity of International Classification of Diseases Codes for Hyponatremia Among Commercially Insured Outpatients in the United States
Should International Classification of Diseases Codes be used to identify outpatient hyponatremia incidence? Uncover what these study authors found in a commercially insured population.
Journal Article, June 2008
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The Lipid Lowering and Onset of Renal Disease (LORD) Trial: a Randomized Double Blind Placebo Controlled Trial Assessing the Effect of Atorvastatin on the Progression of Kidney Disease
How does atorvastatin affect kidney disease progression? Discover more about the relationship between dyslipidemia and chronic kidney disease.
Journal Article, March 2008
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A Systematic Review Of Patient And Health System Characteristics Associated With Late Referral In Chronic Kidney Disease
The aim of this systematic review is to identify patient and health system characteristics associated with late referral of patients with chronic kidney disease to nephrologists.
Journal Article, February 2008
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A Systematic Review Of The Prevalence And Determinants Of Nonadherence To Phosphate Binding Medication In Patients With End-stage Renal Disease
There is a need to establish the level of nonadherence to phosphate binding medication in renal dialysis patients and identify the factors associated with it.
Journal Article, January 2008
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Analgesics Use And ESRD In Younger Age: A Case-control Study
An ad hoc peer-review committee was jointly appointed by Drug Authorities and Industry in 1999/2000 to review the evidence for a causal relation between phenacetin-free analgesics and nephropathy.
Journal Article, December 2007
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Prognosis and Serum Creatinine Levels In Acute Renal Failure at the Time of Nephrology Consultation: An Observational Cohort Study
The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure using the RIFLE criteria.
Journal Article, September 2007
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Clinical Proof-Of-Concept Trial To Assess The Therapeutic Effect Of Sirolimus In Patients With Autosomal Dominant Polycystic Kidney Disease: SUISSE ADPKD Study
The first randomized controlled trial to examine the effectiveness, safety and tolerability of sirolimus to retard disease progression in ADPKD is designed and discussed.
Journal Article, September 2007
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Strategies To Reduce Clinical Inertia In Hypertensive Kidney Transplant Recipients
Many kidney transplant recipients have hypertension. Elevated systolic blood pressures are associated with lower patient and kidney allograft survival.
Journal Article, July 2007
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The Effect of Gender, Age, and Geographical Location on the Incidence and Prevalence of Renal Replacement Therapy in Wales
This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy provision in Wales.
Journal Article, January 2007
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Reliability and Validity of the ESRD Symptom Checklist -- Transplantation Module in Norwegian kidney transplant recipients
The Norwegian version of a questionnaire designed to assess quality of life in kidney transplant recipients, the End-Stage Renal Disease Symptom Checklist -- Transplantation Module is validated.
Journal Article, November 2006
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Would Artificial Neural Networks Implemented in Clinical Wards Help Nephrologists in Predicting Epoetin Responsiveness?
The aim of this study was to re-evaluate the impact of the main parameters know to influence the responsiveness to epoetin beta.
Journal Article, September 2006
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Increased Blood Pressure in Adult Offspring of Families With Balkan Endemic Nephropathy: A Prospective Study
Patients with BEN do not manifest increased blood pressure. The relationship between kidney cortex width, kidney length, and blood pressure in the offspring of BEN patients and controls is evaluated.
Journal Article, August 2006
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Lessons for Medicare Part D in the Hemodialysis Community
By examining the level of understanding and use of the temporary Medicare Prescription Drug Discount Card Program, we can gain a better understanding of the potential long-term utilization for Part D.
Journal Article, July 2006
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Urinary Transforming Growth Factor-Beta 1 as a Marker of Response to Immunosuppressive Treatment, in Patients With Crescentic Nephritis
Can urinary TGF-beta 1 levels in patients with crescentic nephritis could be used as a marker of response to treatment?
Journal Article, April 2006
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Dermatology, March 2006
In this issue: microdermabrasion with and without aluminum oxide crystal abrasion; treating patients with delusions of parasitosis; classifying dermatoses of pregnancy, and more.
Journal Article Commentary, March 2006
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Anemia and Chronic Kidney Disease are Associated With Poor Outcomes in Heart Failure Patients
A retrospective study in 2 Swiss hospitals showed that CKD and anemia are frequent among older patients with heart failure and are predictors of adverse outcomes.
Journal Article, March 2006
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Progressive Neurological Disease Induced by Tacrolimus in a Renal Transplant Recipient: Case Presentation
While mild symptoms such as tremor are well recognised, severe complications including seizures and encephalopathy are poorly documented following renal transplantation.
Journal Article, March 2006