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Delayed Initiation of HIV Care
The initiation of HIV care is most timely when testing occurred at medical facilities, with referrals from nonmedical sites.
AIDS Clinical Care, June 2008
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Enhancing Antiretroviral Activity in the Brain
Can drugs with high CSF penetration treat HIV-associated neurological syndromes more effectively than others?
AIDS Clinical Care, June 2008
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Rifampin and Lopinavir/r: A Combination to Avoid
Learn why you should avoid the concomitant use of Rifampin and Lopinavir/r.
AIDS Clinical Care, May 2008
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Abacavir and ddl Linked to Increased MI Risk
Investigators from the DAD Study reported an unexpected association between recent use of abacavir or ddI and increased risk for myocardial infarction.
AIDS Clinical Care, May 2008
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Low CD4-Cell Counts - Not Just About OI Risk
Will maintaining high CD4-cell counts reduce the risk for AIDS-defining conditions, and also for non-AIDS-defining disease?
AIDS Clinical Care, May 2008
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Both Fish Oil and Fibrates Reduce Triglyceride Levels
Fish oil and fibrates have each been shown to reduce triglyceride levels in HIV-infected patients. However, few comparative data are available.
AIDS Clinical Care, April 2008
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High Immune Activation in Patients With Undetectable Viral Loads and Low CD4-Cell Counts
This article explores low CD4-cell counts among patients who control viral replication without antiretroviral therapy. Is immune activation a possible mechanism for this paradoxical response to HIV?
AIDS Clinical Care, April 2008
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Does Raising Awareness of HIV Serostatus Lower HIV Incidence?
Could an increased awareness of serostatus among people with HIV prevent a rise in the rate of new infections?
AIDS Clinical Care, March 2008
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VA Study: ART Confers Negligible Risk for Heart Disease
Are there any associations between longer durations of ART exposure and risk for heart disease in HIV-infected patients?
AIDS Clinical Care, March 2008
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Circumcision Status and HIV Infection Among MSM in the U.S.
What is the case for circumcision as an HIV-prevention tool among men who have sex with men (MSM) in the U.S.?
AIDS Clinical Care, February 2008
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Clinical Benefit of Continuing a Failing ART Regimen in AIDS Patients
Will the interruption of ART have negative health consequences in patients who have low CD4-cell counts and limited treatment options?
AIDS Clinical Care, January 2008
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Another "When to Start" Cohort Analysis
When is optimal time to start antiretroviral therapy (ART) in asymptomatic HIV-infected patients?
AIDS Clinical Care, January 2008
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A Potential Treatment for HIV-Related Abdominal Obesity
Could tesamorelin, a growth hormone-releasing factor, be a potential treatment for HIV-related abdominal obesity?
AIDS Clinical Care, December 2007
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Virologic Failure: The Roles of Race, Adherence, and Quality of Life
Is race and ethnicity a factor is responses to efavirenz-containing regimens? What could be the clinical importance, given that efavirenz is the recommended NNRTI for initial HIV treatment.
AIDS Clinical Care, December 2007
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How Successful is the Push for Early HIV Diagnosis?
HIV counseling and testing initiatives aim to identify asymptomatic infected persons and refer them for care before the late, symptomatic stages of AIDS. How successful have these initiatives been?
AIDS Clinical Care, November 2007
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Notification of HIV Test Results -- Is the Return Visit Necessary?
HIV testing requires patients to meet with a counselor again to get results but some fail to return. Would more clients receive their test results if they could do so by phone rather than in person?
AIDS Clinical Care, November 2007
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An Unusual Cluster of HIV-associated Kaposi Sarcoma?
HIV-associated Kaposi sarcoma (KS) usually affects patients with low CD4 counts and high viral loads. What accounts for the unusual development of KS in nine HIV patients with good immune function?
AIDS Clinical Care, October 2007
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Directly Administered ART Improves Short-Term Outcomes
Adapting antiretroviral therapy (ART) for direct administration poses challenges. Might monitored dosing of ART be feasible and successful in improving treatment response in HIV-infected drug users?
AIDS Clinical Care, October 2007
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Raltegravir in Treatment-Naive Patients: 48-Week Data
Raltegravir rapidly decreases viral load in treatment-experienced, HIV-infected patients. Might raltegravir have similarly potent effects in treatment-naïve patients after 48 weeks of therapy?
AIDS Clinical Care, September 2007
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Effectiveness of Pneumococcal Vaccine in HIV-Infected Patients
The 23-valent pneumococcal vaccine is recommended for HIV-infected patients with CD4 counts of at least 200 cells/mm3. Is it effective for patients with CD4 counts that are less than 200 cells/mm3?
AIDS Clinical Care, September 2007
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A Quick Blood Test for PCP?
ß-glucan, a fungal cell-wall component, can be present in the sera of persons with overwhelming systemic fungal infection. Might ß-glucan be a good marker of Pneumocystis jiroveci pneumonia infection?
AIDS Clinical Care, August 2007
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Limitations of Rapid Testing
Rapid HIV tests have advantages that lead to their preferred use for HIV screening, especially in many resource-limited settings. But how accurate are the results from sequential rapid HIV testing?
AIDS Clinical Care, July 2007
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Persistence of Neuropsychologic Impairment After Starting ART
Neurocognitive impairment is a complication of advanced HIV infection that potent ART cannot always completely reverse. Persistence of neuropsychological deficits is associated with what factors?
AIDS Clinical Care, July 2007
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Febrile Respiratory Symptoms in HIV: Think Flu
HIV-infected outpatients presenting with fever and respiratory symptoms could have influenza. What is the actual incidence of the flu in such patients and what impact does flu vaccination have?
AIDS Clinical Care, July 2007
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Viral Rebound Rates Decrease Over Time in Suppressed Patients
Viral rebound risk exists for people who've fully suppressed HIV replication. What does UK cohort study data show for rebound rates for suppressed patients with and without treatment failure history?
AIDS Clinical Care, July 2007
