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CME/CE
A Cough in Kentucky
A 46-year-old man presents with a 4-day history of dry cough, fever, chills, night sweats, weight loss, shortness of breath, and easy fatigability. He recently spent time cleaning an abandoned house that had a lot of bird droppings. Chest auscultation reveals fine rales in the mid and lower zones of both lungs. A posteroanterior chest radiograph is obtained. What is the likely diagnosis?
Clinical Review, November 2008
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Failed Connections: Why Connecting Humans Is as Important as Connecting Computers
Daniel Z. Sands, MD, MPH, of Cisco and Harvard Medical School, explains why we need to learn to communicate better.
Editorial, November 2008
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The Delicate Balance Between Hope and Reality
How can clinicians help patients maintain hope, even when further treatments are unlikely to be of benefit? In this video blog, Dr. John Marshall asks when is it time to have the "talk"?
Expert Viewpoint, November 2008
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Influenza: A Multipronged Approach to Protecting Our Smallest Patients
Joanne Langley, MD, MSc, Professor of Pediatrics and Community Health and Epidemiology at Dalhousie University and the IWK Health Centre, explains how to prevent children from catching influenza.
Editorial, November 2008
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Tight Glucose Control in Critically Ill Adults: Is It a Good Idea?
This meta-analysis supports the contention of a growing cadre of physicians that tight glycemic control is not an appropriate strategy in critically ill adults.
Expert Viewpoint, November 2008
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Learning What Works in Healthcare
Harvey V. Fineberg, MD, President, Institute of Medicine, Washington, DC, explains why many should participate in clinical trials.
Editorial, November 2008
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Contrasting Canada and the United States: What Did They Get Right and Wrong About Healthcare?
Jock Murray, MD, Former Dean of Medicine, Dalhousie University, Halifax, Nova Scotia, and Chairman Emeritus, American College of Physicians, compares the US and Canadian systems.
Editorial, November 2008
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CME/CE
Recent Advances in Anticoagulation Therapy
Don't miss this comprehensive update on anticoagulation therapy covering safety issues, new guidelines, and even newer agents.
Clinical Review, November 2008
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Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke: Ranked "Exceptional" from F1000
One of the most important acute stroke trials published since intra-arterial stroke therapies emerged.
Journal Article, November 2008
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Intensive Care Outcomes in Bone Marrow Transplant Recipients: A Population-based Cohort Analysis
The prognosis of bone marrow transplant recipients receiving ICU care during subsequent hospitalizations is very poor, but should it be considered futile?
Journal Article, November 2008
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A Novel Alpha2-Adrenoreceptor Agonist, an Alternative Paradigm for Sedation of Mechanically Ventilated Patients in the ICU: An Expert Interview With Pratik P. Pandharipande, MD, MSCI
The MENDS trial is one of the first studies to show that GABA-sparing agents for sedation are efficacious and safe in mechanically ventilated patients.
Expert Viewpoint, November 2008
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CA-MRSA: How Should We Respond to Outbreaks?
Health Commissioner Emeritus of the Virginia Department of Health answers the question: "How should we respond to outbreaks of CA-MRSA?"
Expert Viewpoint, November 2008
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CME/CE
A 52-Year-Old Woman With Depressed Mentation
A 52-year-old woman accompanied by a family member presents with a 5-day history of headaches, lethargy, nausea, blurred vision, and possible gait disturbance. The patient has a history of breast cancer. Over the course of the office visit, the patient’s neurologic function deteriorates. An emergent CT scan of the head is obtained. What is the reason for the patient’s altered mental status?
Clinical Case, November 2008
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Acute Hemodynamic Effects of Tolvaptan, a Vasopressin V2 Receptor Blocker, in Patients with Symptomatic Heart Failure and Systolic Dysfunction
In decompensated heart failure, tolvaptan, a vasopressin V2 receptor antagonist, has been shown to improve congestion. Are these improvements associated with the hemodynamic effects of tolvaptan?
Journal Article, November 2008
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Chagas Disease: An Expert Interview With Caryn Bern, MD, MPH
Why is Chagas disease considered a newly recognized infectious disease in the United States? How should physicians test and treat patients?
Expert Viewpoint, November 2008
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Is the Clinical Advice You Give Your Patients Evidence-Based?
Carolyn Clancy, MD, Director, Agency for Healthcare Research and Quality, Rockville, Maryland, explains how we can compare treatments for effectiveness.
Editorial, November 2008
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Swallowing Disorders as a Predictor of Unsuccessful Extubation: A Clinical Evaluation
Unsuccessful extubation may be due to a swallowing dysfunction that causes airway obstruction and impairs ability to cough. Would a swallowing assessment before extubation be helpful?
Journal Article, November 2008
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Nefopam for the Prevention of Postoperative Pain: Quantitative Systematic Review
Nefopam, a centrally acting analgesic, has been used in the surgical setting in many countries since the mid-1970s, but what is its role as part of multimodal analgesia?
Journal Article, November 2008
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Cranial Computed Tomographic Findings in a Large Group of Children With Drowning: Diagnostic, Prognostic, and Forensic Implications
This retrospective chart review defines both the type and incidence of cranial computed tomography abnormalities in children following submersion injury.
Journal Article, November 2008
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The Pulmonary Artery Catheter: In Medio Virtus
With an abundance of newer, less invasive technology, is the pulmonary artery catheter still a valuable tool for hemodynamic monitoring?
Journal Article, November 2008