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Modification of Solid Phase Red Cell Adherence Assay for the Detection of Platelet Antibodies in Patients With Thrombocytopenia
Current methods used to detect antiplatelet antibodies have limitations. This modified technique had a sensitivity of 98% and a specificity of 91%.
Journal Article, October 6, 2008
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Precious Last Moments: Family Presence During Resuscitation
Tammie Quest, MD, Director of EPEC -- Emergency Medicine Project -- discusses whether families should observe CPR.
Editorial, October 6, 2008
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Opioids and the Control of Respiration
What are the mechanisms of opioid-induced respiratory depression and how can safer opioid analgesia be achieved? Future research avenues are proposed.
Journal Article, October 3, 2008
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Overexpression of Cathepsin K in Mice Decreases Collagen Deposition and Lung Resistance in Response to Bleomycin-induced Pulmonary Fibrosis
Did the over-expression of cathepsin K reduce lung collagen deposition and improve lung function parameters in the lungs of transgenic mice?
Journal Article, October 3, 2008
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How Should I Treat Acute Bacterial Rhinosinusitis?
Bacterial rhinosinusitis brings many patients into the office, but how many really need antibiotics?
Expert Viewpoint, October 3, 2008
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Doing Better for Less: The Case for Organized Group Practices
Shannon Brownlee, MS, Visiting Scholar, National Institutes of Health, Washington, DC, explains how to both cut healthcare costs and improve quality.
Editorial, October 3, 2008
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European Respiratory Society (ERS) 2008 Annual Congress
Read clinically focused news coverage of key developments from the meeting.
Conference Coverage, October 3, 2008
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CME/CE
The Astute Clinician: Filing High-Value Adverse Drug Event Reports
What information should you include in an ADE report? How is that information used?
Slide/Lecture Presentation, October 3, 2008
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The Role of Peripheral Arterial Disease in the Pathogenesis of Diabetic Foot Disease: When to Refer for Vascular Surgery
The common modes of presentation of patients with diabetes and foot ulcer are discussed.
Journal Article, October 2, 2008
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CME/CE
Osteoporosis After Extrarenal Transplantation: Pathogenesis, Prevention, and Management
The problem of osteoporosis begins before transplantation with end-stage organ disease and is exacerbated by posttransplant immunosuppression.
Clinical Review, October 2, 2008
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Tuberculosis: Vaccines in the Pipeline
The progress of vaccine candidates in animal models to improve, replace or augment BCG vaccination is presented.
Journal Article, October 1, 2008
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Review: Therapeutic Advances in Pulmonary Arterial Hypertension
Numerous studies evaluating prostacyclin agonists, endothelin-receptor antagonists, and phosphodiesterase type 5 inhibitors are available to guide therapeutic choices. Learn more about those studies.
Journal Article, October 1, 2008
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Aerosolized Antibiotics in Cystic Fibrosis: Current and Future Trends
Can aerosolized antibiotics deliver effective local drug concentrations to the infection site and decrease the risk of systemic side effects associated with oral or intravenous antibiotics?
Journal Article, October 1, 2008
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CME/CE
Communicating Drug Risks to Patients
Besides legal concerns, there are many positive reasons to inform patients about the effectiveness and safety of the drugs they are taking.
Clinical Review, September 30, 2008
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Cigarette Smoke Worsens Lung Inflammation and Impairs Resolution of Influenza Infection in Mice
Can the upregulation of pro-inflammatory mediators by short term smoke exposure be protective against a subsequent influenza infection?
Journal Article, September 29, 2008
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Maintaining Remission in a Patient With Vasculitis
In this Case Study, Drs Flossmann and Jayne describe the treatment of a patient with refractory Wegener's granulomatosis, and discuss the challenges associated with managing this disorder.
Journal Article, September 26, 2008
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Severe Asthma Exacerbation: Role of Acute Chlamydophila pneumoniae and Mycoplasma pneumoniae Infection
Is there an association between acute atypical infection and a more severe asthma exacerbation?
Journal Article, September 26, 2008
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Airway Interventions in the Tracheobronchial Tree
This article reviews the advances in endoscopic techniques aimed to the tracheobronchial tree, some of those include foreign body removal, laser photoresection, and electrosurgery.
Journal Article, September 26, 2008
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Innate Immunity to Influenza Virus: Implications for Future Therapy
The implications of burgeoning knowledge of innate immunity for therapy of influenza are discussed.
Journal Article, September 25, 2008
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Exercise-Induced Asthma May Be Associated With Diminished Sweat Secretion Rates in Humans
Do individuals with exercise-induced asthma and excessive bronchiolar reactivity also have decreased muscarinic
receptor-dependent sweat, salivary, and tear gland secretions?
Journal Article, September 25, 2008
